Lead

Found in copper mine tailings as well as old buildings and old water systems [1]

Interferes with neurotransmitter release [2].

Primarily affects dopamine [3]. Lowers dopamine beta hydroxylase [4] which converts dopamine to norepinephrine. This means that people afflicted with chronic lead poisoning likely have elevated dopamine and low norepinephrine.

Lead may also effect serotonin [5]

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