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Several common plants including papaya, fig, and dandelion contain latex with no toxins found. Also the active principle is often cysteine protease [1].

Plant latex can also contain serine proteases and both cysteine and serine proteases show plasmin like activity (digest blood clots). [2]. Plasmin (and plasminogen) is known to treat prion diseases [3] so plant latex is a good vegan medicine for this.

Serine protease in fig digests fibrinogen [4] and activate plasminogen [5].

Both clot inducing and clot dissolving so would be a good additive to a powder or dressing to stop bleeding along with a silica like food grade diatomaceous earth. [6]

Risks

Cystein proteases like Cathepsin K are implicated in bone resorption and gum disease.[7] I am unsure of how this relates to natural cysteine proteases and perhaps these proteases kill the bacteria that release proteases pathogenically? Perhaps looking into protease inhibitors would be better for improving mineralization and gum health?

Also papain removes chondroitin sulfate from cartailage [8] which is probably the reason for supplementation, that bacteria creates excess cysteine protease.

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