Myositis
Inflammation of the muscles that often presents as weak hands and/or wrists and/or shins [1] and can cause wasting of those muscles. Some versions include wasting of quadrecept muscles others do not. Inclusion body myositis is more common in men [2] which seems to spare quadracept muscles until late stages. Absolutely seems to be related to chronic fatigue.
Cause
Usually when something is more present upon waking it means it is a bacteria since the immune system shuts down in sleep especially rem sleep and the bacteria overgrows.
Numerous systemic infections including listeria are capable of inducing myositis [3]
Abnormal intracellular events [4] thus intracellular bacteria might be implicated
Stapylococcus, streptococcus, brucella and numerous other infections implicated [5] [6]. Interesting because I know strep implicated in carpal tunnel and weak hands also goes along with that. But myositis does not necessarily imply wrist pain.
Borrelia, Klebsiella, Mycobacterium can all be causes [7].
Lab tests
List of common labs [8].
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